报告题目：Mechanical Properties and Heterogeneous Growth of Uric Acid Crystals
报 告 人：刘帆 博士（美国乔治城大学）
Fan Liu holds a PhD in chemistry from Georgetown University. His PhD work focused on molecular crystals. He has established the correlation between defects density and mechanical properties, and investigated the non-classical crystal assembly pathway. He did an internship at Boehringer Ingelheim during which he worked on drug substance continuous crystallization engineering.
Most marketed pharmaceuticals consist of active ingredient in crystalline form. The physical properties of those molecular crystals greatly affect the processing and efficacy of solid pharmaceuticals. For example, mechanical properties are important to the formulation and manufacturing of drug substances. Understanding of the interplay between crystal growth, structure and properties has been one of the central goals of crystal engineering. We aim to design crystals with desired physical properties. Crystallization has a significant impact on the final physical properties of drug substance and is considered a critical process step in achieving the continuous manufacturing (CM) of drug substances.