滕昕辰
Xinchen Teng
xcteng@suda.edu.cn
EDUCATION
05/2010 – 09/2013
Postdoctoral fellow in Department of Molecular Microbiology & Immunology, Johns Hopkins University, School of Public Health
09/2004 – 05/2010
Ph.D in Biochemistry, Cellular and Molecular Biology, Johns Hopkins University, School of Medicine
09/2001 – 06/2004
Master in Bioinorganic Chemistry, Fudan University
09/1998 – 06/2001
Bachelor in Chemistry, Fudan University
AWARDS
06/2011 Election to the Phi Beta Kappa Society
03/2009 Keystone Symposia Education Fund Scholarship
09/2004 Fellowship of Johns Hopkins school of Medicine
MEETING PRESENTATIONS
Teng X (Jul. 2010) Invited speaker. Pervasive genetic diversity in the YKO collection reflects gene-specific pressures. Yeast Genetics and Molecular Biology Meeting, University of British Columbia, Vancouver, Canada
Teng X (Oct. 2009) Invited speaker. Evolution of cancer-like mutations that alter nutrient sensing in yeast. Cold Spring Harbor Conference on Cell Death, Cold Spring Harbor, New York, USA
Teng X, Cheng W-C, Leach KM and Hardwick JM (Mar. 2009) Keystone Symposia Education Fund Scholarship Winner.Poster presentation. Evolution of cancer-like mutations in yeast. Keystone Symposia on Cell Death Pathways, Whisler, British Columbia, Canada
Teng X, Cheng W-C, Leach KM and Hardwick JM (Jun. 2008) Poster presentation. Searching for tumor suppressor-like genes in yeast. International Cell Death Symposia, Shanghai, China
Teng X and Hardwick JM (Apr. 2007) Poster presentation. Defining Programmed Cell Death in Yeast. Keystone Symposia on Autophagy and Cell Death Pathways, Monterey, California, USA
Teng X, Yu T, and Hardwick JM (Apr. 2006) Poster presentation. Development of a heat shock assay to detect the anti-death function human Bcl-xL in yeast. Keystone Symposia on Autophagy and Cell Death Pathways, Snowbird, Utah, USA
PUBLICATIONS
Teng X and Hardwick JM (2013), The extrinsic cell death pathway, Molecular Oncology, in press
Teng X, Dayhoff-Brannigan M, Cheng W-C, Gilbert CE, Wheelan SJ, Dunham MJ, Boeke JD, Pineda FJ and Hardwick JM (2013), Genome-wide consequences of deleting any single gene, Molecular Cell, 52, 485-494.
Featured in: SGDNew & Noteworthy, “Gene knockouts may not be so clean after all”,
http://www.yeastgenome.org/gene-knockouts-may-not-be-so-clean-after-all
The Scientist, “One gene two mutations”,
http://www.the-scientist.com/?articles.view/articleNo/38178/title/One-Gene--Two-Mutations/
Teng X and Hardwick JM (2013), Quantification of genetically controlled cell death in budding yeast, Methods in Molecular Biology, 1004, 161-70
Chen YB, Aon MA, Hsu YT, Soane L, Teng X, McCaffery JM, Cheng WC, Qi B, Li H, Alavian KN, Dayhoff-Brannigan M, Zou S, Pineda FJ, O'Rourke B, Ko YH, Pedersen PL, Kaczmarek LK, Jonas EA, Hardwick JM (2011), Bcl-xL regulates mitochondrial energetics by stabilizing the inner membrane potential, J Cell Biol. 195, 263-76
Teng X, Cheng W-C, Qi B, Yu T-X, Ramachandran K, Boersma MD, Hattier T, Lehmann PV, Pineda FJ and Hardwick JM (2011), Gene-dependent cell death in yeast, Cell Death & Disease, 2, e188
Abdelwahid E, Rolland S, Teng X, Conradt B, Hardwick JM and White K (2010) Mitochondrial involvement in cell death of non-mammalian eukaryotes, Biochimica et Biophysica Acta, 1813, 597-607
Teng X and Hardwick JM (2010) The apoptosome at high resolution, Cell, 141, 404-406
Teng X and Hardwick JM (2009) Reliable method for detection of programmed cell death in yeast, Methods in Molecular Biology, 552, 335-342
Ding Z, Teng X, Zheng Q, Ni F, Cai B, Wang Y, Zhou GM, Sun HZ, Tan XS, Huang ZX. (2009) Important roles of the conserved linker-KKS in human neuronal growth inhibitory factor. Biometals, 22:817-26
Cheng W-C, Teng X, Park HK, Tucker CM, Dunham MJ and Hardwick JM (2008) Fis1-deficiency selects for compensatory mutations responsible for cell death and growth control defects, Cell Death and Differentiation, 15, 1838-1846
Ding ZC, Zheng Q, Cai B, Ni FY, Yu WH, Teng X, Gao Y, Liu F, Chen D, Wang Y, Wu HM, Sun HZ, Zhang MJ, Tan XS, Huang ZX. (2008) Study on structure-property-reactivity-function relationship of human neuronal growth inhibitory factor (hGIF). J Inorg Biochem, 102:1965-72
Ding ZC, Zheng Q, Cai B, Yu WH, Teng X, Wang Y, Zhou GM, Wu HM, Sun HZ, Zhang MJ, Huang ZX. (2007) Effect of alpha-domain substitution on the structure, property and function of human neuronal growth inhibitory factor. J Biol Inorg Chem, 12:1173-9
Ding ZC, Teng X, Cai B, Wang H, Zheng Q, Wang Y, Zhou GM, Zhang MJ, Wu HM, Sun HZ, Huang ZX. (2006) Mutation at Glu23 eliminates the neuron growth inhibitory activity of human metallothionein-3. Biochem Biophys Res Commun. 349:674-82
Cai B, Zheng Q, Teng X, Chen D, Wang Y, Wang KQ, Zhou GM, Xie Y, Zhang MJ, Sun HZ, Huang ZX. (2006) The role of Thr5 in human neuron growth inhibitory factor. J Biol Inorg Chem. 11:476-82
Teng X, Zheng Q, Cai B, Ni FY, Xie Y, Sun HZ, Zhang MJ, Huang ZX. (2005) An Insight of S-nitrosylation of human GIF. Chinese Journal of Chemistry, 23: 1545-51
Zheng Q, Yang WM, Yu WH, Cai B, Teng X, Xie Y, Sun HZ, Zhang MJ, Huang ZX. (2003) The effect of the EAAEAE insert on the property of human metallothionein-3. Protein Eng. 16:865-70
Zhou J, Liu Y, Tang L, Teng X, Tang N, Huang ZX. (2003) Interaction of zinc finger ZNF191(243-368) and its I323W and R327W mutants with oligonucleotides by fluorescence spectrum. Science in China, 46: 64-74