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刘艳丽

发布者:金雪明发布时间:2018-11-04浏览次数:1832


姓  名:刘艳丽

职称职务:教授

电子邮箱:liuyanli@suda.edu.cn

办公地址:云轩楼1433

 

个人简介:


一、学习工作经历

1、学历背景

1991.91995.7 沈阳药科大学大学      本科

1999.92002.6 沈阳药科大学药理学硕士生

2002.92005.7 沈阳药科大学药理学博士生

2、工作经历:

2005.122011.6 苏州大学,讲师

2011.72020.6 苏州大学,副教授

2020.7-至今   苏州大学,教授

二、研究方向

1)中药抗炎和抗肿瘤活性成分新靶点的钩钓

2)治疗肾病的中药新活性的发现和机制研究

3)结肠炎治疗候选药物分子的发现和成药性评价研究

 

三、主要研究成果

发表学术论文50余篇,其中SCI论文20余篇,授权中国专利20余项,转让专利8项。作为课题负责人,承担自然科学基金1项,新药创制国家重大专项课题子课题1项,苏州市项目1项,校企合作项目8项。自2006年来,对白头翁、鹿茸草、枸骨、孜然芹等十多种中药进行系统药理活性的研究,发现多种成分的抗炎、抗菌、抗肿瘤等新活性。


四、近五年来发表的主要论文

(1)   Gao HW, Kang NX, Hu C, Zhang ZY, Xu QM, Liu YL*, Yang SLRinsenside Rb1 exerts anti-inflammatory effects in vivo and in vitro by modulating toll like 4 receptor dimerization and NF-kB/MAPKs signaling pathways. Phytomedicine 2020, 69: 153197.

(2)   Feng SX#, Zha ZX#, Wang Z, Yang P, Wu JP, Li X, Xu QM & Liu YL*. Anticancer activity of oleiferoside B involving autophagy and apoptosis through increasing ROS release in MCF-7 cells and SMMC-7721 cells. Natural Product Research, 2020, 18:1-5.

(3)   He L#, Zhang Y#, Kang NX, Wang YE, Zhang ZY, Zha ZX, Yang SL,  Xu QM*, Liu YL*, Anemoside B4 attenuates nephrotoxicity of cisplatin without reducing anti-tumor activity of cisplatinPhytomedicine 2019, 56, 136-146.

(4)       Kang NX#, Shen WH#, Zhang Y, Su ZT, Yang SL, Liu YL*, Xu QM*, Anti-inflammatory and immune-modulatory properties of anemoside B4 isolated from Pulsatilla chinensis in vivoPhytomedicine 2019, 64,152934.

(5)       Kang NX, Yuan RYK, Huang LT, Liu ZJ, Huang D, Huang L, Gao HW*, Liu YL*, Xu QM, Yang SL.Atypical nitrogen-containing flavonoid in the fruits of Cumin (Cuminum cyminum L.) with anti-inflammatory activity, Journal of agricultural and food chemistry 2019, 67, 8339-8347.

(6)   Wu JP#, Li X#, Zhao JP, Wang RJ, Xia ZF, Li XR, Liu YL*, Xu QM*, Khan IA, Yang SL. Anti-inflammatory and cytotoxic withanolides from Physalis minima. Phytochemistry 2018, 155, 164-170.

(7)       Yuan Y#, Pan S#, Yang SL, Liu YL*, Xu QM*. Antioxidant and cardioprotective effects of Ilex cornuta on myocardial ischemia injury. Chinese Journal of Natural Medicines 2017, 15(2), 0094-0104.

(8)   Yu DJ#Li S#Wang S#Li XJZhu MSHuang SSun LZhang YSLiu YL*Wang SL*, Development and characterization of VEGF165-chitosan nanoparticles for the treatment of radiation-induced skin injury in rats, Marine drugs, 2016, 14, e182.

(9)   Wang TY, Zhao JP, Li XR, Xu QM*, Liu YL*, Khan IA, Yang SL, New alkaloids from green vegetable soybeans and their inhibitory activities on the proliferation of concanavalin A-activated lymphocytes, Journal of agricultural and food chemistry2016,64, 1649-1656.