苏州大学药学院欢迎您!

蒋小岗

发布者:金雪明发布时间:2018-11-04浏览次数:1514


电子邮箱:

jiangxiaogang@suda.edu.cn

研究方向:

   肺纤维化药理

研究内容:

肺成纤维细胞分化的机制及药物干预

学习经历:

    1996/091999/06,苏州医学院,专科生,参与中药化学研究

    2001/092004/06,苏州大学,  硕士生,参与中药药理学研究

    2004/092007/06,大连化物所,博士生,参与蛋白质组学研究

工作情况:

    1999/08至现在,苏州大学药理学系

研究论文:

1. Xionghua Sun, Mei Zhu, Xihua Chen, Xiaogang Jiang*.MYH9 inhibition suppresses TGF-β1-stimulated lung fibroblast-to-myofibroblast differentiation. Front. Pharmacol. 2021, 11, 573524.

2. Xionghua Sun, Xinjian Cui, Xihua Chen, Xiaogang Jiang*.Baicalein alleviated TGF β1-induced type I collagen production in lung fibroblasts via downregulation of connective tissue growth factor. Biomed. Pharmacother. 2020, 131, 110744.

3. Fanqing Lu, Xionghua Sun, Xiafang Xu, Xiaogang Jiang*.SILAC-based proteomic profiling of the suppression of TGF-β1-induced lung fibroblast-to-myofibroblast differentiation by trehalose. Toxicol. Appl. Pharmacol., 2020, 391, 114916.

4. Xinjian Cui, Xionghua Sun, Fanqing Lu, Xiaogang Jiang*. Baicalein represses TGF-β1-induced fibroblast differentiation through the inhibition of miR-21. Toxicol. Appl. Pharmacol. 2018, 358, 35-42.

5. Xiang Zhou, Xionghua Sun, Xiaogang Jiang*. Comparative proteome profiling of bleomycin-induced lung toxicity in rats by 2D-nano-LC-MS/MS and spectral counting. Biomed. Chromatogr. 2017, 31e3857.

6. Xionghua Sun, Xiaogang Jiang*.Automated platform of μLC-MS/MS using SAX trap column for highly efficient phosphopeptide analysis. Anal. Bioanal. Chem. 2017, 409, 2489-2493.

7. Yan Gao, Jia Lu, Yu Zhang, Yafen Chen, Zhenlun Gu, Xiaogang Jiang*. Baicalein attenuates bleomycin-induced pulmonary fibrosis in rats through inhibition of miR-21. Pulm. Pharmacol. Ther. 2013, 26, 649-654.

8. Xionghua Sun, Xiaogang Jiang*.Combination of FASP and fully automated 2D-LC-MS/MS allows in-depth proteomic characterization of mouse zymogen granules. Biomed. Chromatogr. 2013, 27, 407-408.