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[12-24]Engineered nanoparticles for cancer imaging and therapy

发布者:金雪明发布时间:2019-12-20浏览次数:217

报告题目:Engineered nanoparticles for cancer imaging and therapy

报 告 人:杨涛 博士Innovation center of nanomedicine

报告时间:20191224日(星期二)上午10:00

报告地点:独墅湖校区二期云轩楼2301会议室 

 

报告人简介:

   Tao Yang obtained his PhD in Pharmaceutical Science from Soochow University in June 2018. His ph.D work in Soochow University was focusing on developing protein nanoreactor for precise cancer imaging-guided phototherapy, which is highly potential for the application in precision medicine and personalized treatment. Currently, as a research scientist at iCONM, he focused primarily on the development of ligand installed PEGylated antibody across BBB for activable brain tumor immunotherapy. So far, Dr. Yang has published over 15 peer-viewed papers in high-class journals in the field of nanomedicine, including published as the first author in Advanced Materials (IF 25.8), ACS Nano (IF 13.9), Theranostics (IF 8.7), Biomaterials (IF 10.3) and so on.

报告摘要:

  Clinically potential proteins such as human serum albumin are utilized as single-molecule nanoreactors for fabrication of size-tunable inorganic nanoparticles or drug-loaded nanoparticles with well-defined nanostructure. The fabrication is accomplished within hollow protein nanocages through biomineralization-mediated controlled growth. These cancer-targeted protein nanoparticles are able to achieve multimodal imaging with both ultrasensitivity and spatial resolution, as well as potent cancer therapy.