Targeted Drug Delivery System and Evauation
Xuenong Zhang
B.S. Xinjiang Medical University, 1983
Ph.D. and Post Doctor Peking University, 2001

Research interests:
1. Controlled release and targetde drug delivery system
2. New technologies and new formulations of drug in nanomedicine
Representative pubilcations:
1. N-Trimethyl Chitosan Nanoparticle-encapsulated Lactosy-Norcantharidin for Liver Cancer Therapy with High Targeting Efficacy.Guan M et a1.Nanomedicine:NBM.2012,8:1172-1181(IF 6.93).
2. Norcantharidin-associated galactosylated chitosan nanoparticles for dual hepatocyte-targetde delivery.Wang Q et a1.Nanomedicine:NBM.2010,6(2):371-381.(IF 6.93).
3. Heoatocyte-targetde delivery using pH-sensitive liposomes loaded with lactosyl-norcantharitin phospholipid complex:preparation,characterization,and therapeutic evaluation in vivo and in vitro.Zhu QL et a1.Curr Med Chem.2012,19(33):5754-5763.
4. Application of the central composite design to optimize the preparation of novel micelles of harmine.Bei YY et a1.Int J Nanomed.2013,8:1795-1808.
5. Effect of alginate-chitosan sustained release microcapsules for transhepatic arterial embolization in VX2 rabbit liver cancer model.ZHANG GY et a1.J Biomed Mater Res A.2013 online:doi:10.1002/jbm.a.34617.
6. The mechanism of polyvinylpyrrolidone-coated norcantharidin chitosan nanoparticles.Ding XY et a1.Curr Nanosci,2013,9,401-406.
7. Analysis of cyclosporine A and its metabolites in rat uring and feces by liquid chromatography-tandem mass spectrometry.Fang ZG et a1.J Chromatography B,2010,878:1153-1162.

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