Design and Evaluation of Functional Drug Delivery System
Lifang Cheng
Associate Professor
B.S. Yangzhou University, Jiangsu, China 2000-2004
Ph.D. Jiangnan University, Jiangsu, China 2004-2010
Visiting Scholar University of North Carolina at Chapel Hill, USA, 2014-2015

1. Design and construction of novel functional drug and gene delivery systems;
2. In vitro and in vivo anti-tumor activity evaluation of novel DDS;
3 Study of intracellular drug transport mechanism.   
SELECTED Peer-reviewed publication 
1. Lifang Cheng, Qin Hu, Lifang Cheng, Lu Zhang, Wen Hu, Ming Xu, Qifu Lei, Yaqin Zhu, Dawei Chen. Construction and Evaluation of PAMAM-DOX Conjugates with Superior Tumor Recognition and Intracellular Acid-Triggered Drug Release Properties. Colloids and surfaces B:Biointerfaces, 2015, accepted.
2. Yaqin Zhu,Liang Cheng,Lifang Cheng,Fazhen Huang,Qin Hu,Ling Li,Chenmin Tian,Lin Wei,Dawei Chen. Folate and TAT peptide co-modified liposomes exhibit receptor-dependent highly efficient intracellular transport of payload in vitro and in vivo. Pharmaceutical Research2014,31(1):3289-3303. 
3. Wen Hu, Liang Cheng, Lifang Cheng, Meng Zheng, Qifu Lei, Ziyang Hu, Ming, Lipeng Qiu, Dawei Chen. Redox and pH-responsive poly (amidoamine) dendrimer–poly (ethylene glycol) conjugates with disulfide linkages for efficient intracellular drug release. Colloids and surfaces B:Biointerfaces, 2014, 123:254-263. (SCI)
4. Liang Cheng, Fazhen Huang, Lifang Cheng, Yaqin Zhu , Qin Hu, Ling Li, Lin Wei, Dawei Chen. GE11-modified liposomes for non-small cell lung cancer targeting: preparation, ex vitro and in vivo evaluation. International Journal of Nanomedicine, 2012, 9: 921-935. 
5. Cheng Lifang, Mu Wanmeng, Jiang Bo. Efficient biotransformation of D-galactose to D-tagatose by Acidothermus cellulolytics ATCC 43068. J Food Biochem, 2011, 35(4):1298-1310.
6. Cheng Lifang, Mu Wanmeng, Zhang Tao, Jiang Bo. An L-arabinose isomerase from Acidothermus cellulolytics ATCC 43068: cloning, expression, purification and characterization. Appl Microbiol Biotechnol, 2010, 86(4):1089–1097.
7. Cheng Lifang, Mu Wanmeng, Jiang Bo. Thermostable L-arabinose isomerase from Bacillus stearothermophilus IAM 11001 for D-tagatose production: gene cloning, purification and characterization. J Sci Food Agri, 2010, 90:1327–1333.
8. Cheng Lifang, Mu Wanmeng, Zhang Tao, Jiang Bo. Cloning, expression and partial characterization of thermostable L-arabinose isomerase from Bacillus stearothermophilus IAM 11001 for D-tagatose preparation. J Biotechnol, 2008, 136S: S741–S742.
1. National Natural Science Foundation of China (Grant No. 81302719, 2014-2016).

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