Pharmaceutical Analysis
 
Liquid chromatography - Mass Spectrometry analysis of complex medicine
Du-Xin Li
Associate Professor
Ph.D. East China University of Science and Technology, 2011;
Duxin.Li@suda.edu.cn
 

Research Interest:
1.Multi-dimensional chromatography mass spectrometry analysis of complex samples;
2.Glycans and Glycoconjugates structure analysis;
3.LC-MS techniques in medicine quality control;
4.Analysis of bioactive components in Chinese Herbal Medicine

Representative publications:
1. Li DX, Dück R, Schmitz OJ. The advantage of mixed-mode separation in the first dimension of comprehensive two-dimensional liquid-chromatography. J Chromatogr A, 2014, 1358:128-135.
2. Li DX, Gan L, Bronja A, Schmitz OJ. Gas chromatography coupled to atmospheric pressure ionization mass spectrometer (GC-API-MS): Review. Anal. Chim. Acta, 2015,891,43-61.
3. Li DX, Schmitz OJ. Use of shift gradient in the second dimension to improve the separation space in comprehensive two-dimensional liquid chromatography. Anal Bioanal Chem, 2013,405(20):1-7. 4. Li DX, Schmitz OJ. Comprehensive two-dimensional liquid chromatography tandem DAD and accurate mass QTOF-MS for the analysis of flavonoids and iridoid glycosides in Hedyotis diffusa. Anal Bioanal Chem, 2015, 407(1): 1-10.
5. Li, DX, Jakob C, Schmitz OJ. Practical considerations in comprehensive two-dimensional liquid chromatography systems (LCxLC) with reversed-phases in both dimensions. Anal Bioanal Chem, 2015, 407(1): 153-167.
6. Li DX, Zhang LY, Wang ZC, Intisar A, Zhang WB. Development of a Parallel-Tandem Column Interface in a Two-Dimensional Liquid Chromatography System. Chromatographia, 2011, 73:  871-877.

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