Microbial and Biochemical Pharmacy
Tumor Immunology
Liang Zhang
B.A. Chinese Pharmaceutical University, 1996
Ph.D. Chinese Pharmaceutical University, 2005

Research interests:
1. Immunology, especially tumor immune evasion
2. Oncology, especially carcinogenesis
Representative publications:
1. The costimulatory molecule B7-H4 promote tumor progression and cell proliferation through  translocating into nucleus. Oncogene, 2013, doi: 10.1038/onc. 2012. 600.
2. CD133 expression in renal cell carcinoma(RCC) is correlated with nuclear hypoxia-inducing  factor 1α(HIF-1α). Journal of Cancer Rwsearch and CLinical Oncology, 2012, 138(10): 1619-1624.
3. Application of the central composite design to optimize the preparation of novel micelles of harmine. International Journal of Nanomedicine, 2013, 8: 1795-1808.
4. Proteomic analysis of clear cell renal cell carcinoma. Saudi Med J, 2010, 31(5): 525-532.
5. Norcantharidin-associated galactosylated chitosan nanoparticles for hepatocyte-targeted delivery. Nanomedicine, 2010. 6(2): 371-81.
6. ACTX-8,a cytotoxic L-amino acid oxidase isolated from Agkistrodon acutus snake venom, induces apoptosis in Hela cervical cancer cells. Life sciences, 2007, 80(13): 1189-1197.
7. A cytotoxin isolated from Agkistrodon acutus snake venom induces apoptosis cia Fas pathway in A549 cells. Toxicology in vitro, 2007,21(6): 1095-1103.
8. Isolation and characterization of ACTX-6:a cytotoxic L-Amino Acid Oxidase from Agkistrodon acutus snake venom. Natural product research,2008, 22(6): 554-563.

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