Microbial and Biochemical Pharmacy
Natural Bioactive Peptides/Proteins
Yipeng Wang
Associate Professor
B.S. Liaocheng University, 2005
Ph.D. Kunming Institute of Zoology, Chinese Academy of Sciences, 2010

Research interests: 
1.  Natural bioactive peptides/proteins discovery
2. Bioactive peptides/proteins design
3. Bioactive peptides/proteins application
Representative publications:
1. Ling G, Gao J, Zhang S, Xie Z, Wei L, Yu H, Wang YP*. Cathelicidins from the bullfrog Rana catesbeiana provides novel template for peptide antibiotic design. PLoS ONE. 2014 27 9(3): e93216.
2. Yu H, Cai S, Gao J, Zhang S, Lu Y, Qiao X, Yang H, Wang YP*. Identification and polymorphism discovery of the cathelicidins, Lf-CATHs in ranid amphibian (Limnonectes fragilis). FEBS J 2013 280(23): 6022-6032.
3. Li Z, Zhang S, Guang H, Gao J, Guo H, He W, Wang YP*, Yu H. Structural and functional characterization of CATH_BRALE, the defense molecule in the ancient salmonoid, Brachymystax lenok. Fish Shellfish Immunol. 2013 34(1): 1-7.
4. He W, Feng F, Huang Y, Guang H, Zhang S, Li Z, Liu J, Wang YP*, Yu H. Host defense peptides in skin secretions of Odorrana tiannanensis: proof for other survival strategy of the frog than merely antimicrobial. Biochimie. 2012 94(3): 649-55.
5. Zhang S, Guo H, Shi F, Wang H, Li L, Jiao X, Wang YP*, Yu H. Hainanenins: A novel family of antimicrobial peptides with strong activity from Hainan cascade-frog, Amolops hainanensis. Peptides. 2012 33(2): 251-7.
6. Wang YP, Zhang Z, Chen L, Guang H, Li Z, Yang H, Li J, You D, Yu H, Lai R. Cathelicidin-BF, a snake cathelicidin-derived antimicrobial peptide, could be an excellent therapeutic agent for acne vulgaris. PLoS ONE. 2011 6(7): e22120.
7. Wang YP, Lu Z, Feng F, Zhu W, Guang H, Liu J, He W, Chi L, Li Z, Yu H. Molecular cloning and characterization of novel cathelicidin-derived myeloid antimicrobial peptide from Phasianus colchicus. Dev Comp Immunol. 2011 35(3): 314-22.
8. Wu J, Wang YP, Liu H, Yang H, Ma D, Li J, Li D, Yu H, Lai R. Two immunoregulatory peptides with antioxidant activity from tick salivary glands. J Biol Chem. 2010 28 285(22): 16606-13. (Co-first author).
9. Ma D, Wang YP, Yang H, Wu J, An S, Gao L, Xu X, Lai R. Anti-thrombosis repertoire of blood-feeding horsefly salivary glands. Mol Cell Proteomics. 2009 8(9): 2071-9. (Co-first author).
10. Wang YP, Hong J, Liu X, Yang H, Liu R, Wu J, Wang A, Lin D, Lai R. Snake cathelicidin from Bungarus fasciatus is a potent peptide antibiotics. PLoS ONE. 2008 16 3(9): e3217.

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