Medicinal Chemistry
Medicinal Chemistry and Organic Chemistry
Shilei Zhang
B.S. Ocean University of China, 2002
Ph.D. Shanghai Institute of Materia Medica,Chinese Academy of Sciences, 2007

Research interests:

(1) Synthetic methodologies

(2) Developing efficient methods to construct privileged structures of drugs.

(3) Design and synthesis of anticancer drugs.

Repeesentative publications:

1.         Mao, Y.; Liu, Y.; Hu, Y.; Wang, L.; Zhang, S.;* Wang, W. “Pd-Catalyzed Debenzylation and Deallylation of Ethers and Esters with Sodium HydrideACS catal., 2018, 8, 3016-3020. (IF=10.614)

2.         Yang, J.; Qiu, G.; Jiang, J.; Hu, Y.;* Chen, S.; Zhang, S.;* Zhang Y. “Asymmetric Organocatalytic Synthesis of Benzopyran- and Benzofuran-Fused Polycyclic AcetalsAdv. Synth. Catal., 2017, 359, 2184-2190. (IF=5.646)

3.         Chen, X.; Zhang, Y.; Wan, H.; Wang, W.; Zhang, S.* “Stereoselective organocatalytic oxidation of alcohols to enals: a homologation method to prepare polyenes” Chem. Commun., 2016, 3532-3535. (IF=6.319)

4.         Liu, S.; Chen, X.; Hu, Y.; Yuan, L.; Chen, S.; Wu, P.; Wang, W.; Zhang, S.;* Zhang, W. “An efficient method for the production of terminal alkynes from 1,1-dibromo-1-alkenes and its application in the total synthesis of natural product dihydroxerulinAdv. Synth. Catal., 2015, 357, 553-560. (IF=5.646)

5.         Zhang, S.-L.; Xie, H.-X.; Zhu, J.; Li, H.; Zhang, X.-S.; Li, J.;* Wang, W.*Organocatalytic enantioselective β-functionalization of aldehydes via oxidation of enamines and their application in cascade reactions  Nature Communications. 2011, 2, 211. (IF=12.124)

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