Medicinal Chemistry
Drug Design and Synthesis
Yongming Zhu
B.S. Soochow University, 1985
Ph.D. Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 1999

Research interests:
1. Design and chemical synthesis of anticancer compounds
2. The methodological investigation on the synthesis of bioactive heterocycles
Representative publicationgs(corresponding author):
1. Copper-Catalyzed C-N Bond Formation/Rearrangement Sequence: Synthesis of  4H-3,1-Benzoxazin-4-ones .Journal of Organic Chemistry,2013,78,4524-4529.
2. Palladium-Catalyzed SYnthesis of Isocoumarins and Phthalides via tert- Butyl Isocyanide Insertion .Journal of Organic Chemistry,2013,78,3170-3175.
3. Palladium-Catalyzed Synthesis of Iso coumarins and Phthalides via tert- Butyl Isocyanide Insertion .Journal of Organic Chemistry,2012,77,10321- 10328.
4. Synthesis of 3-Substitued Isocoumarins via a Cascade Intramolecular  Uiimann-Type Coupling-Rearrangement Pricess .Journal of Organic  Chemistry,2012,77,5736-5743.
5. Cytotoxic Activities and DNA Binding Properties of 1-Methyl -7H-indeno [1,2-b]Quinolinium-7-(4-dimethylamino)Benzylidene Triflate.DNA AND CELL  BIOLOGY,2012,31,1046-1053.

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