朱永明

9.jpg
姓  名:朱永明

职称职务:教授

电子邮箱:zhuyongming@suda.edu.cn

办公地址:云轩楼1438

 

 

个人简介:

一、学习工作经历

1、学历背景:

1981.91985.7 苏州大学 本科

1985.91988.7 苏州大学 硕士生

1996.91999.7 中科院上海药物研究所博士生

2000.32002.3 日本新泻药科大学 博士后研究员

2、工作经历:

1988.81996.8 苏州科技学院 助教、讲师

2002.4-至今 苏州大学副教授、教授

 

二、研究方向

1)抗肿瘤药物的合成和作用机制研究

2)天然物的结构改造及相关活性研究

3)杂环化合物的合成方法研究

 

三、主要研究成果

国内外核心期刊发表论文20余篇,大部分为SCI收录论文。申请国家发明专利4项,参加和主持的项目有国家自然科学基金项目 “功能性离子液体分子的设计和合成以及在有机合成中的应用研究”;教育部留学归国人员启动基金。“吡咯唑[1,5-a]吲哚类化合物的合成及抗肿瘤活性研究”;国家药典委员会项目“蓖麻油质量标准的修订” 。

(一)近期发表的主要论文

1. Qi-Lun Liu, Qiu-Lian Li, Xiang-Dong Fei, Yong-Ming Zhu* Metal-Free    Intramolecular Amination:One-pot Tandem Synthesis of 3-Substituted 4-Quinolones ACS Combinatorial Science 2011 13, 19-23SCI 3.45

2. Chenchen Hang, Qiulian Li, Yongming Zhu*, Hajime Katayama    Copper(I)-Catalyzed Tandem Cyclization Condensation Reaction to Novel 4,5-Dihydropyrazolo[1,5-a]quinolines and Pyrazolo[1,5-a]indoles Synthetic Communications 2011 41, 3318-1124 (SCI 0.96)

3. Qiu-Lian Li, Qi-Lun Liu, Zhi-Yuan Ge, Yong-Ming Zhu* A Novel Synthesis of Isoflavones via Copper(I)-Catalyzed Intramolecular Cyclization Reaction Helvetica Chimica Acta 2011 94, 1304-1309 (SCI 1.45)

4. Zhou-Zhou, Qi-Lun Liu, Wen Li, Yong-Ming Zhu*  A Novel Synthesis of 1-Aryl-1H-Benzotriazoles via Oxidative C-H Amination Heterocycles 2011 83, 9, 2057-2065 (SCI 1.16)

5. Qi-Lun Liu,Di-Di Wen,Chen-Chen Hang,Qiu-Lian Li,Yong-Ming Zhu* A Novel and Regiospecific Synthesis of 1-Aryl-1H-benzotriazoles via Copper(I)-Catalyzed Intramolecular Cyclization Reaction Helvetica Chimica Acta 2010 93 1350-1354(SCI 1.50)

6. Jianwen Chi, Chenchen Hang, Yongming Zhu*, Hajime Katayama  Synthesisof Indolo[1,2-b]indazole Derivatives via Copper(I)-Catalyzed Intra-molecular Amination Reaction Synthetic Communications 2010 40: 1123-1133(SCI 1.01)

7Rui Liu, Yong-ming Zhu* Lie-na Qin, and Shun-jun Ji. Efficient Synthesis of 1-Aryl-1H-Indazoles derivatives via Copper(I)-Catalyzed Intramolecular Amination Reaction. Synthetic Communications 2008 38: 249-254.(SCI 0.98)

8. Yong-Ming Zhu*, Lie-Na Qin, Rui Liu, Shun-Jun Ji, Hajime Katayama. Synthesis of pyrazolo[1,5-a]indoles via copper(I)-catalyzed intramolecular amination Tetrahedron Letters 2007 48: 6262-6266.(SCI 2.66)

9. Rui Liu, Yong-ming Zhu* Lie-na Qin, Shun-jun Ji, Hajime Katayama. Synthesis of 2-Aryl-2H-Indazoles via Copper(I)-Catalyzed Intramolecular Amination Reaction. Heterocycles 2007 71: 1755-1763.( SCI 1.07)

10.Yongming Zhu, Kimiyoshi Kaneko, Osamu Kato, Yoshimitsu Kiryu, Noriyuki Takatsu, Kazuhiko Shiono, and Hajime KatayamaSynthesis of   Indolo[1,2-b]indazole Derivatives Heterocycles 61(2003) 147-162 (SCI 1.07)

11.Yongming  Zhu, Yoshimitsu Kiryu , Hajime KatayamaIntramolecular Aromatic Amination by a Hydrazine Group for the Synthesis of Indolo[1,2,b ] Indazole Derivatives. Tetrahedron Letters 43 (2002) 3577- 3580  (SCI 2.48)

12.Yongming Zhu, Jingkang Shen, Huikang Wang, L.Mark Cosentino , Kuo-Hsiung LeeSynthesis and Anti-HIV Activity of Oleanolic Acid Derivatives. Bioorganic & Medicinal Chemistry Letter. 11(2001)3115-3118. (SCI 2.48)

 

(二)授权专利

1.胆固醇的合成方法及其中间体:ZL200510094762.3

2.吡唑并[15-a]吲哚三氟甲磺酸盐-4-二甲氨基苄烯衍生物及其制备方法 ZL200810156256.6