程丽芳

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姓  名:程丽芳

职称职务:副教授

联系电话:65884729

电子邮箱:Chenglifang@suda.edu.cn

办公地址:云轩楼1524

 

个人简介:

一、学习工作经历

1、学历背景:

2000.92004.7 扬州大学,本科

2004.92010.7 江南大学食品科学与工程国家重点实验室,博士

2、工作经历:

2010.92014.6 苏州大学医学院药学系教研室,讲师

2014.52015.5 美国北卡罗来纳大学教堂山分校药学院,访问学者

2014.7-至今   苏州大学医学院药剂学系教,副教授

 

二、研究方向

1)靶向给药系统的研究

2)功能性高分子载体的研究

3)胞内转运机制的研究

 

三、主要研究成果

1、论文

发表学术论文6篇,其中SCI收录论文4篇。

1. Lifang Cheng, Qin Hu, Lifang Cheng, Lu Zhang, Wen Hu, Ming Xu, Qifu Lei, Yaqin Zhu, Dawei Chen. Construction and Evaluation of PAMAM-DOX Conjugates with Superior Tumor Recognition and Intracellular Acid-Triggered Drug Release Properties. Colloids and surfaces BBiointerfaces, 2015, accepted.
2. Yaqin Zhu
Liang ChengLifang ChengFazhen HuangQin HuLing LiChenmin TianLin WeiDawei Chen. Folate and TAT peptide co-modified liposomes exhibit receptor-dependent highly efficient intracellular transport of payload in vitro and in vivo. Pharmaceutical Research2014311):3289-3303. 
3. Wen Hu, Liang Cheng, Lifang Cheng, Meng Zheng, Qifu Lei, Ziyang Hu, Ming, Lipeng Qiu, Dawei Chen. Redox and pH-responsive poly (amidoamine) dendrimer–poly (ethylene glycol) conjugates with disulfide linkages for efficient intracellular drug release. Colloids and surfaces B
Biointerfaces, 2014, 123:254-263. (SCI)
4. Liang Cheng, Fazhen Huang, Lifang Cheng, Yaqin Zhu , Qin Hu, Ling Li, Lin Wei, Dawei Chen. GE11-modified liposomes for non-small cell lung cancer targeting: preparation, ex vitro and in vivo evaluation. International Journal of Nanomedicine, 2012, 9: 921-935. 
5. Cheng Lifang, Mu Wanmeng, Jiang Bo. Efficient biotransformation of D-galactose to D-tagatose by Acidothermus cellulolytics ATCC 43068. J Food Biochem, 2011, 35(4):1298-1310.
6. Cheng Lifang, Mu Wanmeng, Zhang Tao, Jiang Bo. An L-arabinose isomerase from Acidothermus cellulolytics ATCC 43068: cloning, expression, purification and characterization. Appl Microbiol Biotechnol, 2010, 86(4):1089–1097.
7. Cheng Lifang, Mu Wanmeng, Jiang Bo. Thermostable L-arabinose isomerase from Bacillus stearothermophilus IAM 11001 for D-tagatose production: gene cloning, purification and characterization. J Sci Food Agri, 2010, 90:1327–1333.
8. Cheng Lifang, Mu Wanmeng, Zhang Tao, Jiang Bo. Cloning, expression and partial characterization of thermostable L-arabinose isomerase from Bacillus stearothermophilus IAM 11001 for D-tagatose preparation. J Biotechnol, 2008, 136S: S741–S742.

2、课题

1)国家自然科学基金青年基金,81302719具靶向穿膜与内涵体逃逸功能的新型聚酰胺-siRNA递送系统的构建及抗肿瘤研究,2014/01-2016/12,主持。

2)苏州大学青年自然科学基金,Q313203111 L-阿拉伯糖异构酶的底物特异性机制及其分子改造,2011/03-2013/03,主持,已结题 。

3)国家自然基金,81202473HER2抗体介导的pH敏感光交联聚合物胶束递药系统的构建及抗肿瘤研究, 2013/01-2015/12, 主要参与,排名第二。