邓益斌

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    名:邓益斌

职称职务:副教授

电子邮箱:ybyi@suda.edu.cn

办公地址:云轩楼1333

 

个人简介

 

一、学习工作经历

 

1、学历背景:

2009.9 - 2013.7       德国慕尼黑大学化学与药学学院,药物技术与生物医药,博士

2006.9 - 2009.7       复旦大学高分子科学系,高分子化学与物理,硕士

2002.9 - 2006.7       中山大学化学与化学工程学院,材料化学,本科

 

2、工作经历:

2016.10至今:苏州大学药学院药物制剂系,副教授

2013.9 - 2016.9:苏州大学药学院药物制剂系,讲师

 

二、研究方向

 

研究兴趣主要包含以下几个方面:

1)纳米药物载体;

2)多肽、蛋白质等生物大分子类药物的制剂与传输

 

三、主要研究成果

 

发表学术论文10篇,授权专利1项,申请专利1项:

研究论文:

[1]             Y Wang,# Y Deng,# H Luo,# A Zhu, H Ke, H Yang, H Chen*. Light-responsive nanoparticles for highly efficient cytoplasmic delivery of anticancer agents, ACS Nano, 2017, 11, 12134-12144. (#co-first author)

[2]             T Yang, H Ke, Q Wang, Y Tang, Y Deng*, H Yang, X Yang, P Yang, D Ling, C Chen, Y Zhao, H Wu*, H Chen*. Bifunctional tellurium nanodots for photo-induced synergistic cancer therapy, ACS Nano, 2017, 11, 10012-10024. (*corresponding author)

[3]             H Luo,# Q Wang,# Y Deng,# T Yang, H Ke, H Yang, H He, Z Guo, D Yu, H Wu, H Chen*. Mutually synergistic nanoparticles for effective thermo-molecularly targeted therapy, Adv Funct Mater, 2017, 27, 1702834. (#co-first author)

[4]             T Yang, L Liu, Y Deng, Z Guo, G Zhang, Z Ge*, H Ke*, H Chen*. Ultrastable near-infrared conjugated polymer nanoparticles for dually photoactive tumor inhibition, Adv Mater, 2017, 29, 1700487.

[5]             Y Deng,# L Huang,# H Yang*, H Ke, H He, Z Guo, T Yang, A Zhu, H. Wu*, H Chen*. Cyanine-anchored Silica Nanochannels for Light-Driven Synergistic Thermo-Chemotherapy. Small. 2017, 13, 1602747. (#co-first author)

[6]             Y. Li#, Y. Deng#, X. Tian#, H. T. Ke, M. Guo, A. J. Zhu, T. Yang, Z. Q. Guo, Z. S. Ge, X. L. Yang, H. B. Chen. Multipronged Design of Light-Triggered Nanoparticles To Overcome Cisplatin Resistance for Efficient Ablation of Resistant Tumor. ACS Nano, 2015, 9: 9626-9637 (#co-first author)

[7]             A. J. Zhu, K. Miao, Y. B. Deng, H. T. Ke, H. He, T. Yang, M. Guo, Y. L. Li, Z. Q. Guo, Y. Y. Wang, X. L. Yang, Y. L. Zhao, H. B. Chen. Dually pH/Reduction-Responsive Vesicles for Ultrahigh-Contrast Fluorescence Imaging and Thermo-Chemotherapy-Synergized Tumor Ablation. ACS Nano, 2015, 9: 7874-7885

[8]             M. Guo, J. Huang, Y. B. Deng, H. Shen, Y. F. Ma, M. X. Zhang, A. J. Zhu, Y. L. Li, H. He, Y. Y. Wang, X. L. Yang, Z. J. Zhang, H. B. Chen, pH-Responsive Cyanine-Grafted Graphene Oxide for Fluorescence Resonance Energy Transfer-Enhanced Photothermal Therapy. Adv. Funct. Mater., 2015, 25: 59-67

[9]             Yibin Deng, Gerhard Winter, Julia Myschik. Encapsulation of Antigen-loaded Silica Nanoparticles into Microparticles for Intradermal Powder Injection. Eur. J. Pharm. Sci., 2014, 63: 154-166

[10]         Yibin Deng, Gerhard Winter, Julia Myschik. Preparation and Validation of a Skin Model for the Evaluation of Intradermal Powder Injection Devices. Eur. J. Pharm. Biopharm., 2012, 81(2): 360-368

[11]         Yibin Deng, Jian-Hua Cai, Ping Zhou. Naturally Stable Free Radical in the Silk Fibroin and Its Structure Environment Studied by EPR and DFT. Spectrosc. Lett., 2012, 45(4): 285-295

[12]         Yibin Deng, Dan Ji, Jianhua Cai, Ping Zhou. The Role of Mn(II) in Silk Fibroin Based on EPR and NMR Spectroscopy. Spectrosc. Lett., 2011, 44(3): 176-185

[13]         Yibin Deng, Bingwen Hu, Ping Zhou. Solid-State NMR Studies of Structures and Molecular Motions for the Spidroin-Like Copolymers. Acta Phys.-Chim. Sin., 2009, 25(7): 1427-1433

[14]         Dan Ji, Yibin Deng, Ping Zhou. Folding process of silk fibroin induced by ferric and ferrous ions. J. Mol. Struct., 2009, 938: 305-310

[15]         邓益斌, 季丹, 周平. 磁共振技术在丝素蛋白结构与功能研究中的应用. 波谱学杂志, 2008, 25: 555-572

 

专利:

[1]             陈华兵、杨涛、邓益斌、汪勇、柯亨特、郭正清、何慧、杨红、邹烨璘、计双双、汪巧莉,具有近红外光热效应的铜基人血白蛋白纳米复合物及其制备方法,CN105106958A

[2]             陈华兵,邓益斌,杨红,柯亨特,黄丽,朱爱军,郭正清. 具有近红外光热和体内荧光成像特性的多功能介孔二氧化硅纳米粒及其制备方法和应用. 专利申请号:21510490341.6.

[3]             Gerhard Winter, Julia Engert, Yibin Deng. Nano-in-micro particles for intradermal delivery, 国际专利号:WO 2015/110656 A1

 

主持科研项目

 

1. 国家自然科学基金青年基金项目“用于肿瘤协同治疗的近红外光响应性硅纳米粒的研究”(31500811),2015-2018

 

2. 江苏省自然科学基金青年基金“近红外光响应性硅纳米粒的构建及其肿瘤协同治疗研究”(BK20150324),2015-2018