Copper-Catalyzed C–N Bond Formation/Rearrangement Sequence: Synthesis of 4H-3,1-benzoxazin-4-ones.
Zhi-Yuan Ge, Qiong-Ming Xu, Xiang-Dong Fei, Ting Tang, Yong-Ming Zhu,* and Shun-Jun Ji.
J. Org. Chem. IF4.564, 2013, 78, 4524−4529.
A facile and efficient copper-catalyzed method for the synthesis of 4H-3,1-benzoxazin-4-one derivatives has been developed. This procedure is based on a tandem intramolecular C–N coupling/rearrangement process. This method would provide a new and useful strategy for construction of N-heterocycles.