Xiaogang Jiang

Department of Pharmacology

Email: jiangxiaogang@suda.edu.cn

Biosketch

q  Education

M. S. Soochow University, 2004
Ph.D. Dalian Institute of Chemical Physics, CAS, 2007

q  Work experience

1999-present  Soochow University

Research Interests

q  Respiratory Pharmacology and Toxicology

1.      The effect and mechanism of active compounds on lung myofibroblast differentiation

2.      The effect and mechanism of drug-induced lung epithelial cells injury

Research Fund

National Natural Science Foundation of China

Select Publications

1. Mei Zhu, Jian Zhang, Xionghua Sun^*, Xihua Chen, Xiaogang Jiang^*. Eupafolin suppresses TGF-β1-induced human lung fibroblasts differentiation by downregulating β-catenin/plasminogen activator inhibitor-1 signaling. Pharmacological Research-Modern Chinese Medicine, 2022, 2, 100056.

2. Meng Li, Yadong Cui,Mei Zhu, Xiaolei Huang, Faiz UrRehmana, Jingwen Wang,  Lixiao Zhang, Tianwen Liu, Jiangyun Liu, Junye Lu, Xiaogang Jiang*, Jian Zhang*. Isolation and characterization of secondary metabolites from the leaves of Sauropus spatulifolius Beille and their potential biological assays. Fitoterapia. 2022, 156, 105100.

3. Xiafang Xu, Xionghua Sun, Xuelei Wan, Xihua Chen, Xiaogang Jiang*. Mitomycin induces alveolar epithelial cell senescence by down-regulating GSK3β signaling. Toxicology Letters, 2021, 352, 61-69.

4. Xionghua Sun, Mei Zhu, Xihua Chen, Xiaogang Jiang*.MYH9 inhibition suppresses TGF-β1-stimulated lung fibroblast-to-myofibroblast differentiation. Frontiers in Pharmacology, 2021, 11, 573524.

5. Xionghua Sun, Xinjian Cui, Xihua Chen, Xiaogang Jiang*.Baicalein alleviated TGF β1-induced type I collagen production in lung fibroblasts via downregulation of connective tissue growth factor. Biomedicine & Pharmacotherapy, 2020, 131, 110744.

6. Fanqing Lu, Xionghua Sun, Xiafang Xu, Xiaogang Jiang*.SILAC-based proteomic profiling of the suppression of TGF-β1-induced lung fibroblast-to-myofibroblast differentiation by trehalose. Toxicology and Applied Pharmacology, 2020, 391, 114916.

7. Xinjian Cui, Xionghua Sun, Fanqing Lu, Xiaogang Jiang*. Baicalein represses TGF-β1-induced fibroblast differentiation through the inhibition of miR-21. Toxicology and Applied Pharmacology, 2018, 358, 35-42.

8. Xiang Zhou, Xionghua Sun, Xiaogang Jiang*. Comparative proteome profiling of bleomycin-induced lung toxicity in rats by 2D-nano-LC-MS/MS and spectral counting. Biomedical Chromatography, 2017, 31，e3857.

9. Yan Gao, Jia Lu, Yu Zhang, Yafen Chen, Zhenlun Gu, Xiaogang Jiang*. Baicalein attenuates bleomycin-induced pulmonary fibrosis in rats through inhibition of miR-21. Pulmonary Pharmacology & Therapeutics, 2013, 26, 649-654.