Chaonan Zheng

Chaonan Zheng, Ph.D

Lecturer

College of Pharmaceutical Science

Email: zhengcn@suda.edu.cn

Biosketch

q  Education

Sep 2005~Jul 2010  PhD inPharmacokinetics, China Pharmaceutical University, China

Sep 2001~Jul 2005  BSc in Pharmaceutical Science,China Pharmaceutical University,China

q  Work experience

Nov 2016~present   College of Pharmaceutical Science, Soochow University, China

Jun 2013~Apr 2016  Postdoc, Albrecht-Kossel-Institute for Neuroregeneration (AKos), University of Rostock, Germany

Feb 2013~Jun 2013  Postdoc, Proteome Center Rostock, University of Rostock, Germany

Aug 2010~Jan 2011  Senior scientific researcher, DMPK Dept., Shanghai Pharma.

Research Interests

q  Identification of new targets for the therapy of brain cancer in children

q  Establishment of high throughput screening model for anti-cancer molecules

q  Drug drug interaction in the combined therapy for medulloblastoma

Research Fund

2019/01-2021/12    National Science Foundation for Young Scientists of China (Grant No. 81803616): Synergistic effect of cholesterol biosynthesis inhibitor and Smo antagonist for the treatment of Shh-medullob

Select Publications

(1) Fan, Qianhai; Gong, Tingting; Zheng, Chaonan; Ng, Jessica M. Y.; Chen, Jianquan; Myers, Cynthia; Hensley, Harvey; Curran, Tom; Yang, Zeng-jie ; Statins repress hedgehog signaling in medulloblastoma with no bone toxicities, Oncogene, 2021, 40(40): 2258-2272

(2) Yan, Cheng; Janusz, Franco-Barraza; Yuan, Wang; Chaonan, Zheng; Li, Zhang; Yanghui, Qu; Yaqiu, Long; Edna, Cukierman; Zeng-jie, Yang ; Sustained hedgehog signaling in medulloblastoma tumoroids is attributed to stromal astrocytes and astrocyte-derived extracellular matrix, Laboratory Investigation, 2020, 100(9): 1208-1222

(3) Wang, Hua; Dong, Yanan; Zheng, Chaonan; Sandoval, Christian A.; Wang, Xue; Makha, Mohamed; Li, Yuehui ; Catalytic Cyanation Using CO2 and NH3, Chem, 2018, 4(12): 2883-2893

(4) Du, Fang; Yuelling, Larra; Lee, Eric H; Wang, Yuan; Liao, Shengyou; Cheng, Yan; Zhang, Li; Zheng, Chaonan; Peri, Suraj; Cai, Kathy Q; Ng, Jessica M Y; Curran, Tom; Li, Peng; Yang, Zeng Jie ; Leukotriene Synthesis Is Critical for Medulloblastoma Progression, Clinical Cancer Research, 2019, 25(21): 6475-6486

(5) Chaonan Zheng; Haiping Hao; Xuan Wang; Xiaolan Wu; Guangji Wang; Guowei Sang; Yan Liang; Lin Xie; Chunhua Xia; Xilin Yao ; Diagnostic fragment-ion-based extension strategy for rapid screening and identification of serial components of homologous families contained in traditional Chinese medicine prescription using high-resolution LC-ESI- IT-TOF/MS: Shengmai injection as an example, Journal of Mass Spectrometry, 2008, 44: 230-244