李盛亮

发布者:金雪明发布时间:2022-07-05浏览次数:7294



 

   名:李盛亮

职称职务:博士,特聘教授,博士生导师

国家级青年人才计划获得者

江苏特聘教授(重点资助)获得者

姑苏创新领军人才(青年)获得者

电子邮箱:lishengliang@suda.edu.cn

办公地址:云轩楼2101(office)、云轩楼2113, 2115, 1410(lab)

 

个人简介:

李盛亮,特聘教授,博士生导师。2012-2016年,博士和博士后阶段师从国家纳米科学中心梁兴杰和中国科学院化学研究所王树研究员分别从事纳米医学和生物光子领域研究学习,随后于2016-2021年分别在马萨诸塞州立大学医学院、康奈尔大学休士顿卫理公会研究所以及香港城市大学从事博士后和高级副研究工作。20211月加入苏州大学药学院,被聘为特聘教授、博士生导师,担任先进光子与纳米医学实验室负责人。入选国家级海外高层次人才、江苏特聘教授(重点资助)、姑苏创新青年领军人才等国家及省市项目。近年来聚焦研究领域已发表高水平SCI论文90余篇,其中包括以第一或通讯作者在Adv. Mater., Angew. Chem. In. Ed., ACS Nano等国际权威刊物上发表的论文50余篇,其中ESI高被引论文4篇。申请 PCT 国际专利 4项,获授权中国专利 4 项,参与撰写2本纳米材料领域书籍。同时长期担任Angew. Chem. In. Ed., Adv. Mater., ACS Nano, Adv. Funt. Mater.30余个国际期刊的独立审稿人。

 

研究方向:

针对未被满足的医学需求进行多学科深度交叉性前沿研究,研究主要聚焦于光学药物与探针、纳米药物范畴,通过设计和构建光活性材料体系发展光---声性能可转换的新型纳米医药技术,以此实现精准与高效低毒的重大疾病治疗、生物成像和生物活性调控。

1.  光活性药物与探针

2.  药物递送与诊疗应用

3.  智能诊疗器件与生物材料开发

 

 

招聘信息:

 

博士后:拟招收2-3名从事药物合成、药学递送、生物医学等专业的博士后研究人员,要求能够独立开展研究工作,具有良好的英文写作与交流能力,易于沟通。具有有机化学、生物材料或药剂学背景的申请者优先考虑。待遇优厚,且有机会到国外交流访学和联合培养。如有兴趣,请联系lishengliang@suda.edu.cn

 

青年研究团队成员:拟招聘1-2名课题组青年研究人员(副教授/副研究员/助理研究员等),要求获得(或即将获得)博士学位,具有药物合成、生物材料或药剂学背景,在主流期刊上发表过SCI论文,能够独立开展研究。有意向者请发送简历至lishengliang@suda.edu.cn

 

代表性论文:

1.       Yi Yuan,† Zhe Feng,† Shengliang Li,* Zhongming Huang, Yingpeng Wan, Chen Cao, Sien Lin, Lan Wu, Jing Zhou, Liang-Sheng Liao, Jun Qian,* and Chun-Sing Lee*, Molecular Programming of NIR-IIb-Emissive Semiconducting Oligomers for In Vivo High-Contrast Bioimaging Beyond 1500 nm. Adv. Mater. 2022, 34, 2201263. (IF: 32.086

2.       Shuang Tian, Jihua Tan, Tianxing Kang, Chen Cao, Jie Pan, Yafang Xiao, Xiao Cui, Shengliang Li,* Chun-Sing Lee*, Harnessing Polymer Matrix-Mediated Manipulation of Intermolecular Charge-Transfer for Near-Infrared Security Applications. Adv. Mater. 2022, 34, 2204749. (IF: 32.086

3.       Xiaozhen Li,† Di Zhang,† Guihong Lu*, Tingchao He, Yingpeng Wan, Man-Kit Tse, Can Ren, Pengfei Wang, Shengliang Li*, Jingdong Luo*, Chun-Sing Lee*, Photochemical Synthesis of Nonplanar Small Molecules with Ultrafast Nonradiative Decay for Highly Efficient Phototheranostics. Adv. Mater. 2021, 33, 202102799. (IF: 32.086

4.       Shengliang Li, Qingyuan Deng, Yachao Zhang, Xiaozhen Li, Guohua Wen, Xiao Cui, Yingpeng Wan, Yongwei Huang,* Jiaxiong Chen, Zhonghua Liu, Lidai Wang,* and Chun-Sing Lee*, Rational Design of Conjugated Small Molecules for Superior Photothermal Theranostics in NIR-II Biowindow. Adv. Mater. 2020, 32, 2001146. (IF: 32.086

5.       Yunxia Wang, Shengliang Li,* Pengbo Zhang, Haotian Bai, Liheng Feng, Fengting Lv, Libing Liu,* and Shu Wang* Photothermal-Responsive Conjugated Polymer Nanoparticles for Remote Control of Gene Expression in Living Cells. Adv. Mater. 2018, 30: 1705418.IF: 32.086

6.       Shuang Tian,† Haotian Bai,† Shengliang Li*, Yafang Xiao, Xiao Cui, Xiaozhen Li, Jihua Tan, Zhongming Huang, Dong Shen, Weimin Liu, Pengfei Wang, Ben Zhong Tang*, Chun-Sing Lee*, Water‐Soluble Organic Nanoparticles with Programable Intermolecular Charge‐Transfer for NIR‐II Photothermal Anti‐Bacterial Therapy. Angew. Chem. Int. Ed. 2021, 133, 11864.IF: 16.823

7.       Huan Chen, Shengliang Li,* Min Wu, Kenry, Zhongming Huang, Chun-Sing Lee,* and Bin Liu,* Membrane-Anchoring Photosensitizer with Aggregation-Induced Emission Characteristics for Combating Multidrug‐Resistant Bacteria. Angew. Chem. Int. Ed. 2020, 59, 632.IF: 16.823

8.       Shengliang Li, Tao Chen, Yunxia Wang, Yanyi Huang,* Kirk S. Schanze,* and Shu Wang*, Conjugated Polymer with Intrinsic Alkyne Units for Synergetically Enhanced Raman Imaging in Living Cells. Angew. Chem. Int. Ed. 2017, 56, 13455.IF: 16.823

9.       Shengliang Li*, Xiangquan Deng, Hui Cheng, Xiaozhen Li, Yingpeng Wan, Chen Cao, Jie Yu, Ying Liu, Yi Yuan, Ke Wang*, and Chun-Sing Lee*, Bright Near-Infrared π-Conjugated Oligomer Nanoparticles for Deep-Brain Three-Photon Microscopy Excited at the 1700 nm Window in Vivo. ACS Nano 2022, 16, 12480. IF: 18.027

10.   Shengliang Li, Haoting Chen, Haile Liu, Qiankun Ni, Yuan Yuan, Cong Mao, Wei Zhang, Xiaodong Zhang, Weisheng Guo*, Chun-Sing Lee*, and Xing-Jie Liang*, In Vivo Real-Time Evaluation on Pharmaceutical Behavior of PEGylated-Nanomedicine with intrinsic Near-Infrared II Fluorescence. ACS Nano 2020, 14, 13681. IF: 18.027

11.   Yingpeng Wan, Guihong Lu, Wei-Chih Wei, Yi-Hsuan Huang, Shengliang Li,* Jia-Xiong Chen, Xiao Cui, Ya-Fang Xiao, Xiaozhen Li, Yanhong Liu, Xiang-Min Meng, Hai-Yan Xie, Jinfeng Zhang,* Ken-Tsung Wong,* and Chun-Sing Lee*, Stable Organic Photosensitizer Nanoparticles with Absorption Peak beyond 800 nm and High ROS Yield for Multi-Modality Phototheranostics. ACS Nano 2020, 14, 9917. IF: 18.027

12.   Xiaozhen Li, Lu Liu,Shengliang Li,* Yingpeng Wan, Jia-Xiong Chen, Shuang Tian, Zhongming Huang, Ya-Fang Xiao, Xiao Cui, Chengyang Xiang, Xiao-hong Zhang, Weisheng Guo,* Xing-Jie Liang, and Chun-Sing Lee.* Biodegradable π-Conjugated Oligomer Nanoparticles with High Photothermal Conversion Efficiency for Cancer Theranostics. ACS Nano 2019, 13, 12901.IF: 18.027

13.   Xiaoxiao Fan, Yirun Li, Zhe Feng, Guoqiao Chen, Jing Zhou, Mubin He, Lan Wu, Shengliang Li,* Jun Qian,* Hui Lin*, Nanoprobes-assisted multi-channel NIR-II fluorescence imaging-guided resection and photothermal ablation of lymph nodes. Adv. Sci. 2021, 8, 2003972. IF: 17.521

14.   Xiao Cui, Shengzhi Dong, Shengliang Li,* Jinfeng Zhang, Yafang Xiao, Yanhong Liu, Xiangmin Meng, Feng Li,* and Chun-Sing Lee*, Stable π-Radical Nanoparticles as Versatile Photosensitizer for Effective Hypoxia-Overcoming Photodynamic Therapy. Mater. Horiz. 2020, 8, 571.IF: 15.717

15.   Ning Li, Yijian Gao, Boying Li, Dong Gao, Hao Geng, Shengliang Li*, and Chengfen Xing*, Remote Manipulation of ROS-Sensitive Calcium Channel Using Near-Infrared-Responsive Conjugated Oligomer Nanoparticles for Enhanced Tumor Therapy In Vivo. Nano Lett. 2022, 22, 5427.IF: 12.262

 

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