欧阳艺兰

发布者:金雪明发布时间:2019-07-13浏览次数:2741




欧阳艺兰

苏州大学药学院讲师(y_ouyang@suda.edu.cn),苏州大学优秀青年学者,分别于2013年、2016年、2019年获得黑龙江大学制药工程工学学士学位、苏州大学药物分析硕士和博士学位。2017-2018年赴美伦斯勒理工学院联合培养。主要研究方向是肝素类药物的结构分析与糖类药物的研究与开发。2020年荣获江苏省“双创博士”。

近五年承担的科研项目

1. 国家自然科学基金青年项目(82003708),基于毛细管电泳质谱联用技术(CE-MS)的非抗凝肝素序列解析及其抗炎构效关系研究,2021.01-2023.12,主持。

2. 国家自然科学基金面上项目81673388),肝素类药物糖组学研究,2017.01-2020.12,参与。

3. 国家自然科学基金面上项目(81473179,复杂蛋白聚糖的序列分析,2015.01-2018.12,参与。

近五年代表论文

1. N. Yan, X. Li, C. Zhou, Q. Jiang, J. Li, Z. Zhang, Y. Ouyang*, D. Li*, J. Li*; Characterization of degradation products of carrageenan by LC-QTOFMS with a hypothetical database, Food Chemistry, 2022, 384: 132504.2,  IF:7.5

2. L. Chen; Y. Ouyang; N. Yan; Y. Guo; L. Yi; Y. Sun; D. Liu; Z. Zhang*; Comprehensive analysis of heparinase derived heparin-products using two-dimensional liquid chromatography coupled with mass spectrometry, Journal of Chromatography A, 2021, 1643: 462042-462049. 2,  IF:4.6

3. L. Chen, W. Zhu, N. Yan, Y. Guo, L. Yi, Y. Ouyang*, Z. Zhang*; Analysis of heparinase derived LMWH products using a MHC 2D LC system linked to Q-TOF MS, Journal of Pharmaceutical and Biomedical Analysis, 2022, 212:114616-114323. 3,  IF:3.6

4. Y. Ouyang, M. Zhu, X.Wang, L. Yi, Y. Yao, J. Fareed, R. J Linhardt*, Z. Zhang,* Systematic analysis of enoxaparins from different sources with online one and two-dimensional chromatography, Analyst. 2019, 144, 3746-3755.2区,IF:5.2

5. Y. Ouyang, Y. Yu, F. Zhang, J. Chen, X. Han, K. Xia, Y.Yao, Z. Zhang,* R.J. Linhardt*, Non-Anticoagulant Low Molecular Weight Heparins for Pharmaceutical Applications, Journal Medicinal Chemistry, 2019, 62, 1067-1073.2区,IF:8.0.

6. Y. Ouyang, X. Han, Q. Xia, J. Chen, S. Velagapudi, K. Xia,Z. Zhang* and R.J Linhardt* Negative-ion Mode Capillary Isoelectric Focusing-Mass Spectrometry for Charge-Based Separation of Acidic Oligosaccharides, Analytical Chemistry, 2019, 91, 846-853.  1, IF:8.0

7. Y. Ouyang, X. Han, Y. Yu, J. Chen, L. Fu, F. Zhang, R. Linhardt, J. Fareed, D. Hoppensteadt, W. Jeske, A. Kouta, Z. Zhang,* K. Xia*. Chemometric analysis of porcine, bovine and ovine heparins, Jounral of Pharmaceutical and Biomedical Analysis, 2019, 164, 345-352. 3,  IF:3.6

8. Y. Ouyang, Y. Zeng, L. Yi, H. Tang, D. Li, R. Linhardt, Z. Zhang* Qualitative and quantitative analysis of heparin and low molecular weight heparins using size exclusion chromatography with multiple angle laser scattering/refractive index and inductively coupled plasma/mass spectrometry detectors, Journal of Chromatography A. 2017, 1522(3): 56-61. 2,  IF:4.6