[9-29]Pharmaceutical Nanobiotechnology: Basic and Applications

报告题目：Pharmaceutical Nanobiotechnology: Basic and Applications
                  —Naturally-derived nanomaterials for drug delivery and regenerative medicine
报 告 人：王永中 博士（Ohio State University）
报告时间：2014年9月29日（星期一）上午9:00
报告地点：独墅湖校区二期云轩楼2301室
 
报告摘要
Next generation nanomedicine will rely on not only new potent drugs, but innovative nanomaterials with smart delivery capability and biocompatibility in vivo. With near endless diversity in unique physicochemical properties, promising biocompatibility, and potential use in disease treatment and prevention, naturally-derived organic nanomaterials offer an opportunity to fabricate these novel nanomedicines. To develop more effective and smart nanobiomaterials for various biomedical applications, we learned the basic principles from nature at nano-scales. Here we report four naturally-derived nanoparticles from fungus and plants, including fungal nanoparticles (FNPs), tea nanoparticles (TNPs), ivy nanoparticles (INPs) and sundew nanofibers (SNFs). FNPs were secreted from a carnivorous fungus cultured in a liquid media; TNPs were isolated from green tea infusions; INPs were generated and collected from rootles of a creeping plant, English ivy; and SNFs were derived from leaves of a carnivorous plant Sundew. By examining and characterizing the chemical and physical properties of these naturally-derived nanoparticles, the potential applications in fields of drug delivery and tissue engineering have been evaluated and envisioned. This research opened a new avenue for natural nanomaterial development in the context of biomedical applications, especially for drug delivery and regenerative medicine.

 
报告人简介
Dr. Yongzhong Wang is a visiting associate professor at Ohio State University (Columbus, OH). He is currently focusing on research and development of novel pharmaceutical nanobiotechnology. His research activities span a wide range of areas:1) the discovery and development of naturally-derived nanomaterials for drug delivery and tissue engineering; 2) peptide, lipid and polymer-based drug delivery system for cancer therapy; 3) bio-inspired nanobiotechnology platform using peptide-based nanomaterials or semiconductor/metal- based nanostructrues for nanodiagnostics; 4) development of recombinant peptide/protein drugs and microbial-derived drugs/metabolites.
Dr. Wang earned a PhD degree in pharmaceutics from Fudan University in 2007. His graduate studies centered on drug-resistant cancer therapy using polymer-based micelles. After that he became an associate professor in Anhui University. Three years later he joined Professor Yan’s lab at Auburn University as a postdoctoral fellow, then he moved to The University of Tennessee at Knoxville working in Dr. Zhang’s lab as a research associate. Currently, Dr. Wang continues working as a visiting associate professor in Dr. Zhang’s lab at Ohio State University, where he is focusing on the study of naturally-derived nanomaterials and bio-inspired nanomaterials for drug delivery, tissue engineering and nanodiagnostics.