报告题目:Protein Synthesis Defects in Infectious and Neurological Diseases
报 告 人:Ass. Prof. Jiqiang Ling
Department of Microbiology and Molecular Genetics
University of Texas Health Science Center at Houston
报告时间:2015年11月30日(星期一)上午10:00
报告地点:独墅湖校区二期云轩楼2301室
报告摘要:
Protein synthesis is a central process in all cells. Decreased translational rate and fidelity cause cell death and neurodegeneration. A rapidly increasing number of mutations in the protein synthesis machinery have been identified to cause peripheral and central neuropathies in human patients, and the pathogenic mechanisms are only beginning to be understood. In addition, the protein synthesis machinery is heavily targeted by antibiotics to treat infectious diseases. The rising threat of antibiotic resistance calls for a better understanding of how antibiotics work and how pathogens survive antimicrobial treatment. In this lecture, Dr. Ling will discuss the mechanisms and disease connections of protein synthesis defects.